ExplainabilityAccountabilityFairnesscs.CV
Interpretation of Deep Learning Model in Embryo Selection for In Vitro Fertilization (IVF) Treatment
Radha Kodali, Venkata Rao Dhulipalla, Venkata Siva Kishor Tatavarty, Madhavi Nadakuditi, Bharadwaj Thiruveedhula, Suryanarayana Gunnam, Durga Prasad Bavirisetti, Gogulamudi Pradeep Reddy
June 7, 2025
arXiv.org
5 citations
Key Takeaways
-
AI can improve embryo selection efficiency: The study demonstrates that deep learning models can classify embryos with high accuracy, potentially reducing the time-consuming manual review process currently performed by embryologists and making IVF treatment more accessible.
-
Interpretability is crucial for medical AI applications: The researchers specifically designed their system using explainable AI (XAI) techniques, recognizing that doctors and patients need to understand why the AI makes specific recommendations about embryo selection rather than simply trusting a "black box" decision.
-
Combining multiple AI approaches improves results: The study uses a CNN-LSTM architecture (combining convolutional neural networks with long short-term memory networks), suggesting that hybrid approaches may be more effective for analyzing complex medical images like blastocysts than single-method solutions.
-
Automated embryo grading addresses a real clinical bottleneck: The paper identifies that current expert-based embryo grading is both time-consuming and inconsistent, indicating that AI assistance could help standardize care and potentially improve outcomes for people undergoing fertility treatment.
-
Medical AI requires both accuracy and transparency: This work exemplifies responsible AI development in healthcare by pursuing not just high accuracy but also maintaining interpretability—ensuring that AI tools used in reproductive medicine can be validated and understood by medical professionals before being trusted with consequential decisions.
Abstract
Infertility has a considerable impact on individuals' quality of life, affecting them socially and psychologically, with projections indicating a rise in the upcoming years. In vitro fertilization (IVF) emerges as one of the primary techniques within economically developed nations, employed to address the rising problem of low fertility. Expert embryologists conventionally grade embryos by reviewing blastocyst images to select the most optimal for transfer, yet this process is time-consuming and lacks efficiency. Blastocyst images provide a valuable resource for assessing embryo viability. In this study, we introduce an explainable artificial intelligence (XAI) framework for classifying embryos, employing a fusion of convolutional neural network (CNN) and long short-term memory (LSTM) architecture, referred to as CNN-LSTM. Utilizing deep learning, our model achieves high accuracy in embryo classification while maintaining interpretability through XAI.
Paper Info
arXiv ID2506.06680
PublishedJune 7, 2025
RevisedAugust 28, 2025
Citations
5
Relevance75%
VenuearXiv.org
TypeJournalArticle, Review
Categorycs.CV
Responsible AI Topics
ExplainabilityAccountabilityFairness
Links
Citation data from Semantic Scholar