ExplainabilityTransparencyTrustworthinesscs.SD
XAI-Driven Spectral Analysis of Cough Sounds for Respiratory Disease Characterization
Patricia Amado-Caballero, Luis Miguel San-José-Revuelta, María Dolores Aguilar-García, José Ramón Garmendia-Leiza, Carlos Alberola-López, Pablo Casaseca-de-la-Higuera
August 20, 2025
arXiv.org
2 citations
1 influential
Key Takeaways
-
XAI makes AI decisions understandable: The paper demonstrates that explainable AI techniques (specifically "occlusion maps") can reveal which parts of cough sound recordings the AI model actually uses to make decisions, rather than treating the model as a "black box." This transparency is crucial for building trust in AI-driven medical tools.
-
Interpretability revealed patterns that raw data missed: When researchers analyzed cough spectrograms weighted by the AI's attention areas, they found significant differences between disease groups—particularly in COPD patients—that were invisible when analyzing the raw sound data directly. This suggests XAI can uncover clinically meaningful patterns that standard analysis overlooks.
-
Disease-specific acoustic signatures exist: The study identified that COPD patients show more variable cough patterns in specific frequency regions of sound recordings. This finding could eventually enable non-invasive respiratory disease diagnosis through cough analysis alone, potentially reducing the need for more invasive testing.
-
Explainability improves diagnostic reliability: By making the AI's reasoning process visible and connecting it to actual spectral features, this approach provides clinicians with interpretable results they can validate and understand, rather than relying on unexplained algorithmic predictions—essential for responsible deployment in healthcare.