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TumorXAI: Self-Supervised Deep Learning Framework for Explainable Brain MRI Tumor Classification
Abrar Hossain Zahin, Amit Kumar Saha, Tanvir Mridha, Saifur Rahman, Jannatul Ferdous Prome, Raima Husna, Israt Jahan, Ahmed Wasif Reza
May 3, 2026
arXiv.org
Key Takeaways
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Self-supervised learning can work with unlabeled medical data: The study demonstrates that AI models can be effectively trained on MRI images without requiring extensive manual labeling by doctors, which is particularly valuable since annotated medical datasets are scarce and expensive to create.
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High accuracy achieved across multiple tumor types: SimCLR achieved 99.64% accuracy in classifying 17 distinct brain tumor types from 4,448 MRIs, suggesting the approach could potentially assist clinicians in early diagnosis and treatment planning.
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Explainability techniques make AI decisions transparent: The research incorporated three explainability methods (Grad-CAM, Grad-CAM++, EigenCAM) that provide "visual insights into model decisions," allowing doctors to see which parts of the MRI the AI is analyzing—a critical requirement for responsible medical AI deployment.
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SSL outperforms traditional supervised learning when labels are limited: When training data with labels is scarce, self-supervised learning models showed better performance across all metrics (accuracy, precision, recall, F1-score) compared to standard supervised approaches, making this method more practical for real-world medical settings.
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Addresses a real clinical challenge: By handling tumor heterogeneity and working with limited annotated data, this framework tackles genuine obstacles that have previously restricted AI adoption in brain tumor diagnosis.