Research Papers

This study explores the potential of utilizing administrative claims data, combined with advanced machine learning and deep learning techniques, to predict the progression of Chronic Kidney Disease (CKD) to End-Stage Renal Disease (ESRD). We analyze a comprehensive, 10-year dataset provided by a major health insurance organization to develop prediction models for multiple observation windows using traditional machine learning methods such as Random Forest and XGBoost as well as deep learning approaches such as Long Short-Term Memory (LSTM) networks. Our findings demonstrate that the LSTM model, particularly with a 24-month observation window, exhibits superior performance in predicting ESRD progression, outperforming existing models in the literature. We further apply SHapley Additive exPlanations (SHAP) analysis to enhance interpretability, providing insights into the impact of individual features on predictions at the individual patient level. This study underscores the value of leveraging administrative claims data for CKD management and predicting ESRD progression.

Gender bias in machine translation (MT) systems poses significant challenges that often result in the reinforcement of harmful stereotypes. Especially in the labour domain where frequently occupations are inaccurately associated with specific genders, such biases perpetuate traditional gender stereotypes with a significant impact on society. Addressing these issues is crucial for ensuring equitable and accurate MT systems. This paper introduces a novel approach to studying occupation-related gender bias through the creation of the GOSt-MT (Gender and Occupation Statistics for Machine Translation) Knowledge Graph. GOSt-MT integrates comprehensive gender statistics from real-world labour data and textual corpora used in MT training. This Knowledge Graph allows for a detailed analysis of gender bias across English, French, and Greek, facilitating the identification of persistent stereotypes and areas requiring intervention. By providing a structured framework for understanding how occupations are gendered in both labour markets and MT systems, GOSt-MT contributes to efforts aimed at making MT systems more equitable and reducing gender biases in automated translations.

Perturbation-based post-hoc image explanation methods are commonly used to explain image prediction models. These methods perturb parts of the input to measure how those parts affect the output. Since the methods only require the input and output, they can be applied to any model, making them a popular choice to explain black-box models. While many different methods exist and have been compared with one another, it remains poorly understood which parameters of the different methods are responsible for their varying performance. This work uses the Randomized Input Sampling for Explanations (RISE) method as a baseline to evaluate many combinations of mask sampling, segmentation techniques, smoothing, attribution calculation, and per-segment or per-pixel attribution, using a proxy metric. The results show that attribution calculation, which is frequently the focus of other works, has little impact on the results. Conversely, segmentation and per-pixel attribution, rarely examined parameters, have a significant impact. The implementation of and data gathered in this work are available online: https://github.com/guspih/post-hoc-image-perturbation and https://bit.ly/smooth-mask-perturbation.

While AI has been frequently applied in the context of immigration, most of these applications focus on selection and screening, which primarily serve to empower states and authorities, raising concerns due to their understudied reliability and high impact on immigrants' lives. In contrast, this paper emphasizes the potential of AI in Canada's immigration settlement phase, a stage where access to information is crucial and service providers are overburdened. By highlighting the settlement sector as a prime candidate for reliable AI applications, we demonstrate its unique capacity to empower immigrants directly, yet it remains under-explored in AI research. We outline a vision for human-centred and responsible AI solutions that facilitate the integration of newcomers. We call on AI researchers to build upon our work and engage in multidisciplinary research and active collaboration with service providers and government organizations to develop tailored AI tools that are empowering, inclusive and safe.

AI prevails in financial fraud detection and decision making. Yet, due to concerns about biased automated decision making or profiling, regulations mandate that final decisions are made by humans. Financial fraud investigators face the challenge of manually synthesizing vast amounts of unstructured information, including AI alerts, transaction histories, social media insights, and governmental laws. Current Visual Analytics (VA) systems primarily support isolated aspects of this process, such as explaining binary AI alerts and visualizing transaction patterns, thus adding yet another layer of information to the overall complexity. In this work, we propose a framework where the VA system supports decision makers throughout all stages of financial fraud investigation, including data collection, information synthesis, and human criteria iteration. We illustrate how VA can claim a central role in AI-aided decision making, ensuring that human judgment remains in control while minimizing potential biases and labor-intensive tasks.

Understanding the inner representation of a neural network helps users improve models. Concept-based methods have become a popular choice for explaining deep neural networks post-hoc because, unlike most other explainable AI techniques, they can be used to test high-level visual "concepts" that are not directly related to feature attributes. For instance, the concept of "stripes" is important to classify an image as a zebra. Concept-based explanation methods, however, require practitioners to guess and manually collect multiple candidate concept image sets, making the process labor-intensive and prone to overlooking important concepts. Addressing this limitation, in this paper, we frame concept image set creation as an image generation problem. However, since naively using a standard generative model does not result in meaningful concepts, we devise a reinforcement learning-based preference optimization (RLPO) algorithm that fine-tunes a vision-language generative model from approximate textual descriptions of concepts. Through a series of experiments, we demonstrate our method's ability to efficiently and reliably articulate diverse concepts that are otherwise challenging to craft manually.

Deep Reinforcement Learning (DRL) is a frequently employed technique to solve scheduling problems. Although DRL agents ace at delivering viable results in short computing times, their reasoning remains opaque. We conduct a case study where we systematically apply two explainable AI (xAI) frameworks, namely SHAP (DeepSHAP) and Captum (Input x Gradient), to describe the reasoning behind scheduling decisions of a specialized DRL agent in a flow production. We find that methods in the xAI literature lack falsifiability and consistent terminology, do not adequately consider domain-knowledge, the target audience or real-world scenarios, and typically provide simple input-output explanations rather than causal interpretations. To resolve this issue, we introduce a hypotheses-based workflow. This approach enables us to inspect whether explanations align with domain knowledge and match the reward hypotheses of the agent. We furthermore tackle the challenge of communicating these insights to third parties by tailoring hypotheses to the target audience, which can serve as interpretations of the agent's behavior after verification. Our proposed workflow emphasizes the repeated verification of explanations and may be applicable to various DRL-based scheduling use cases.

The increasing use of Retrieval-Augmented Generation (RAG) systems in various applications necessitates stringent protocols to ensure RAG systems accuracy, safety, and alignment with user intentions. In this paper, we introduce VERA (Validation and Evaluation of Retrieval-Augmented Systems), a framework designed to enhance the transparency and reliability of outputs from large language models (LLMs) that utilize retrieved information. VERA improves the way we evaluate RAG systems in two important ways: (1) it introduces a cross-encoder based mechanism that encompasses a set of multidimensional metrics into a single comprehensive ranking score, addressing the challenge of prioritizing individual metrics, and (2) it employs Bootstrap statistics on LLM-based metrics across the document repository to establish confidence bounds, ensuring the repositorys topical coverage and improving the overall reliability of retrieval systems. Through several use cases, we demonstrate how VERA can strengthen decision-making processes and trust in AI applications. Our findings not only contribute to the theoretical understanding of LLM-based RAG evaluation metric but also promote the practical implementation of responsible AI systems, marking a significant advancement in the development of reliable and transparent generative AI technologies.

Despite many advances in knowledge engineering (KE), challenges remain in areas such as engineering knowledge graphs (KGs) at scale, keeping up with evolving domain knowledge, multilingualism, and multimodality. Recently, KE has used LLMs to support semi-automatic tasks, but the most effective use of LLMs to support knowledge engineers across the KE activites is still in its infancy. To explore the vision of LLM copilots for KE and change existing KE practices, we conducted a multimethod study during a KE hackathon. We investigated participants' views on the use of LLMs, the challenges they face, the skills they may need to integrate LLMs into their practices, and how they use LLMs responsibly. We found participants felt LLMs could contribute to improving efficiency when engineering KGs, but presented increased challenges around the already complex issues of evaluating the KE tasks. We discovered prompting to be a useful but undervalued skill for knowledge engineers working with LLMs, and note that natural language processing skills may become more relevant across more roles in KG construction. Integrating LLMs into KE tasks needs to be mindful of potential risks and harms related to responsible AI. Given the limited ethical training, most knowledge engineers receive solutions such as our suggested `KG cards' based on data cards could be a useful guide for KG construction. Our findings can support designers of KE AI copilots, KE researchers, and practitioners using advanced AI to develop trustworthy applications, propose new methodologies for KE and operate new technologies responsibly.

In this paper we investigate the explainability of transformer models and their plausibility for hate speech and counter speech detection. We compare representatives of four different explainability approaches, i.e., gradient-based, perturbation-based, attention-based, and prototype-based approaches, and analyze them quantitatively with an ablation study and qualitatively in a user study. Results show that perturbation-based explainability performs best, followed by gradient-based and attention-based explainability. Prototypebased experiments did not yield useful results. Overall, we observe that explainability strongly supports the users in better understanding the model predictions.

Dementia, a debilitating neurological condition affecting millions worldwide, presents significant diagnostic challenges. In this work, we introduce DEFORMISE, a novel DEep learning Framework for dementia diagnOsis of eldeRly patients using 3D brain Magnetic resonance Imaging (MRI) scans with Optimized Slice sElection. Our approach features a unique technique for selectively processing MRI slices, focusing on the most relevant brain regions and excluding less informative sections. This methodology is complemented by a confidence-based classification committee composed of three novel deep learning models. Tested on the Open OASIS datasets, our method achieved an impressive accuracy of 94.12%, surpassing existing methodologies. Furthermore, validation on the ADNI dataset confirmed the robustness and generalizability of our approach. The use of explainable AI (XAI) techniques and comprehensive ablation studies further substantiate the effectiveness of our techniques, providing insights into the decision-making process and the importance of our methodology. This research offers a significant advancement in dementia diagnosis, providing a highly accurate and efficient tool for clinical applications.

Explaining Decisions in ML Models: a Parameterized Complexity Analysis

Sebastian Ordyniak, Giacomo Paesani, Mateusz Rychlicki +1

This paper presents a comprehensive theoretical investigation into the parameterized complexity of explanation problems in various machine learning (ML) models. Contrary to the prevalent black-box perception, our study focuses on models with transparent internal mechanisms. We address two principal types of explanation problems: abductive and contrastive, both in their local and global variants. Our analysis encompasses diverse ML models, including Decision Trees, Decision Sets, Decision Lists, Ordered Binary Decision Diagrams, Random Forests, and Boolean Circuits, and ensembles thereof, each offering unique explanatory challenges. This research fills a significant gap in explainable AI (XAI) by providing a foundational understanding of the complexities of generating explanations for these models. This work provides insights vital for further research in the domain of XAI, contributing to the broader discourse on the necessity of transparency and accountability in AI systems.