Research Papers

This study provides an in_depth analysis of the ethical and trustworthiness challenges emerging alongside the rapid advancement of generative artificial intelligence (AI) technologies and proposes a comprehensive framework for their systematic evaluation. While generative AI, such as ChatGPT, demonstrates remarkable innovative potential, it simultaneously raises ethical and social concerns, including bias, harmfulness, copyright infringement, privacy violations, and hallucination. Current AI evaluation methodologies, which mainly focus on performance and accuracy, are insufficient to address these multifaceted issues. Thus, this study emphasizes the need for new human_centered criteria that also reflect social impact. To this end, it identifies key dimensions for evaluating the ethics and trustworthiness of generative AI_fairness, transparency, accountability, safety, privacy, accuracy, consistency, robustness, explainability, copyright and intellectual property protection, and source traceability and develops detailed indicators and assessment methodologies for each. Moreover, it provides a comparative analysis of AI ethics policies and guidelines in South Korea, the United States, the European Union, and China, deriving key approaches and implications from each. The proposed framework applies across the AI lifecycle and integrates technical assessments with multidisciplinary perspectives, thereby offering practical means to identify and manage ethical risks in real_world contexts. Ultimately, the study establishes an academic foundation for the responsible advancement of generative AI and delivers actionable insights for policymakers, developers, users, and other stakeholders, supporting the positive societal contributions of AI technologies.

Enhancing XAI Interpretation through a Reverse Mapping from Insights to Visualizations

Aniket Nuthalapati, Nicholas Hinds, Brian Y. Lim +1

As AI systems become increasingly integrated into high-stakes domains, enabling users to accurately interpret model behavior is critical. While AI explanations can be provided, users often struggle to reason effectively with these explanations, limiting their ability to validate or learn from AI decisions. To address this gap, we introduce Reverse Mapping, a novel approach that enhances visual explanations by incorporating user-derived insights back into the explanation workflow. Our system extracts structured insights from free-form user interpretations using a large language model and maps them back onto visual explanations through interactive annotations and coordinated multi-view visualizations. Inspired by the verification loop in the visualization knowledge generation model, this design aims to foster more deliberate, reflective interaction with AI explanations. We demonstrate our approach in a prototype system with two use cases and qualitative user feedback.

We introduce Advertisement Embedding Attacks (AEA), a new class of LLM security threats that stealthily inject promotional or malicious content into model outputs and AI agents. AEA operate through two low-cost vectors: (1) hijacking third-party service-distribution platforms to prepend adversarial prompts, and (2) publishing back-doored open-source checkpoints fine-tuned with attacker data. Unlike conventional attacks that degrade accuracy, AEA subvert information integrity, causing models to return covert ads, propaganda, or hate speech while appearing normal. We detail the attack pipeline, map five stakeholder victim groups, and present an initial prompt-based self-inspection defense that mitigates these injections without additional model retraining. Our findings reveal an urgent, under-addressed gap in LLM security and call for coordinated detection, auditing, and policy responses from the AI-safety community.

Recognizing the need for explainable AI (XAI) approaches to enable the successful integration of AI-based ECG prediction models (AI-ECG) into clinical practice, we introduce a framework generating \textbf{Co}unter\textbf{F}actual \textbf{E}CGs (i,e., named CoFE) to illustrate how specific features, such as amplitudes and intervals, influence the model's predictive decisions. To demonstrate the applicability of the CoFE, we present two case studies: atrial fibrillation classification and potassium level regression models. The CoFE reveals feature changes in ECG signals that align with the established clinical knowledge. By clarifying both \textbf{where valid features appear} in the ECG and \textbf{how they influence the model's predictions}, we anticipate that our framework will enhance the interpretability of AI-ECG models and support more effective clinical decision-making. Our demonstration video is available at: https://www.youtube.com/watch?v=YoW0bNBPglQ.

A precise assessment of the risk of breast lesions can greatly lower it and assist physicians in choosing the best course of action. To categorise breast lesions, the majority of current computer-aided systems only use characteristics from mammograms. Although this method is practical, it does not completely utilise clinical reports' valuable information to attain the best results. When compared to utilising mammography alone, will clinical features greatly enhance the categorisation of breast lesions? How may clinical features and mammograms be combined most effectively? In what ways may explainable AI approaches improve the interpretability and reliability of models used to diagnose breast cancer? To answer these basic problems, a comprehensive investigation is desperately needed. In order to integrate mammography and categorical clinical characteristics, this study examines a number of multimodal deep networks grounded on feature concatenation, co-attention, and cross-attention. The model achieved an AUC-ROC of 0.98, accuracy of 0.96, F1-score of 0.94, precision of 0.92, and recall of 0.95 when tested on publicly accessible datasets (TCGA and CBIS-DDSM).

PASS: Probabilistic Agentic Supernet Sampling for Interpretable and Adaptive Chest X-Ray Reasoning

Yushi Feng, Junye Du, Yingying Hong +2

Existing tool-augmented agentic systems are limited in the real world by (i) black-box reasoning steps that undermine trust of decision-making and pose safety risks, (ii) poor multimodal integration, which is inherently critical for healthcare tasks, and (iii) rigid and computationally inefficient agentic pipelines. We introduce PASS (Probabilistic Agentic Supernet Sampling), the first multimodal framework to address these challenges in the context of Chest X-Ray (CXR) reasoning. PASS adaptively samples agentic workflows over a multi-tool graph, yielding decision paths annotated with interpretable probabilities. Given the complex CXR reasoning task with multimodal medical data, PASS leverages its learned task-conditioned distribution over the agentic supernet. Thus, it adaptively selects the most suitable tool at each supernet layer, offering probability-annotated trajectories for post-hoc audits and directly enhancing medical AI safety. PASS also continuously compresses salient findings into an evolving personalized memory, while dynamically deciding whether to deepen its reasoning path or invoke an early exit for efficiency. To optimize a Pareto frontier balancing performance and cost, we design a novel three-stage training procedure, including expert knowledge warm-up, contrastive path-ranking, and cost-aware reinforcement learning. To facilitate rigorous evaluation, we introduce CAB-E, a comprehensive benchmark for multi-step, safety-critical, free-form CXR reasoning. Experiments across various benchmarks validate that PASS significantly outperforms strong baselines in multiple metrics (e.g., accuracy, LLM-Judge, semantic similarity, etc.) while balancing computational costs, pushing a new paradigm shift towards interpretable, adaptive, and multimodal medical agentic systems.

Medico 2025: Visual Question Answering for Gastrointestinal Imaging

Sushant Gautam, Vajira Thambawita, Michael Riegler +2

The Medico 2025 challenge addresses Visual Question Answering (VQA) for Gastrointestinal (GI) imaging, organized as part of the MediaEval task series. The challenge focuses on developing Explainable Artificial Intelligence (XAI) models that answer clinically relevant questions based on GI endoscopy images while providing interpretable justifications aligned with medical reasoning. It introduces two subtasks: (1) answering diverse types of visual questions using the Kvasir-VQA-x1 dataset, and (2) generating multimodal explanations to support clinical decision-making. The Kvasir-VQA-x1 dataset, created from 6,500 images and 159,549 complex question-answer (QA) pairs, serves as the benchmark for the challenge. By combining quantitative performance metrics and expert-reviewed explainability assessments, this task aims to advance trustworthy Artificial Intelligence (AI) in medical image analysis. Instructions, data access, and an updated guide for participation are available in the official competition repository: https://github.com/simula/MediaEval-Medico-2025

Monitoring cattle health and optimizing yield are key challenges faced by dairy farmers due to difficulties in tracking all animals on the farm. This work aims to showcase modern data-driven farming practices based on explainable machine learning(ML) methods that explain the activity and behaviour of dairy cattle (cows). Continuous data collection of 3-axis accelerometer sensors and usage of robust ML methodologies and algorithms, provide farmers and researchers with actionable information on cattle activity, allowing farmers to make informed decisions and incorporate sustainable practices. This study utilizes Bluetooth-based Internet of Things (IoT) devices and 4G networks for seamless data transmission, immediate analysis, inference generation, and explains the models performance with explainability frameworks. Special emphasis is put on the pre-processing of the accelerometers time series data, including the extraction of statistical characteristics, signal processing techniques, and lag-based features using the sliding window technique. Various hyperparameter-optimized ML models are evaluated across varying window lengths for activity classification. The k-nearest neighbour Classifier achieved the best performance, with AUC of mean 0.98 and standard deviation of 0.0026 on the training set and 0.99 on testing set). In order to ensure transparency, Explainable AI based frameworks such as SHAP is used to interpret feature importance that can be understood and used by practitioners. A detailed comparison of the important features, along with the stability analysis of selected features, supports development of explainable and practical ML models for sustainable livestock management.

This paper maps Africa's distinctive AI risk profile, from deepfake fuelled electoral interference and data colonial dependency to compute scarcity, labour disruption and disproportionate exposure to climate driven environmental costs. While major benefits are promised to accrue, the availability, development and adoption of AI also mean that African people and countries face particular AI safety risks, from large scale labour market disruptions to the nefarious use of AI to manipulate public opinion. To date, African perspectives have not been meaningfully integrated into global debates and processes regarding AI safety, leaving African stakeholders with limited influence over the emerging global AI safety governance agenda. While there are Computer Incident Response Teams on the continent, none hosts a dedicated AI Safety Institute or office. We propose a five-point action plan centred on (i) a policy approach that foregrounds the protection of the human rights of those most vulnerable to experiencing the harmful socio-economic effects of AI; (ii) the establishment of an African AI Safety Institute; (iii) promote public AI literacy and awareness; (iv) development of early warning system with inclusive benchmark suites for 25+ African languages; and (v) an annual AU-level AI Safety & Security Forum.

Can AI Explanations Make You Change Your Mind?

Laura Spillner, Rachel Ringe, Robert Porzel +1

In the context of AI-based decision support systems, explanations can help users to judge when to trust the AI's suggestion, and when to question it. In this way, human oversight can prevent AI errors and biased decision-making. However, this rests on the assumption that users will consider explanations in enough detail to be able to catch such errors. We conducted an online study on trust in explainable DSS, and were surprised to find that in many cases, participants spent little time on the explanation and did not always consider it in detail. We present an exploratory analysis of this data, investigating what factors impact how carefully study participants consider AI explanations, and how this in turn impacts whether they are open to changing their mind based on what the AI suggests.

Traditional surgical skill acquisition relies heavily on expert feedback, yet direct access is limited by faculty availability and variability in subjective assessments. While trainees can practice independently, the lack of personalized, objective, and quantitative feedback reduces the effectiveness of self-directed learning. Recent advances in computer vision and machine learning have enabled automated surgical skill assessment, demonstrating the feasibility of automatic competency evaluation. However, it is unclear whether such Artificial Intelligence (AI)-driven feedback can contribute to skill acquisition. Here, we examine the effectiveness of explainable AI (XAI)-generated feedback in surgical training through a human-AI study. We create a simulation-based training framework that utilizes XAI to analyze videos and extract surgical skill proxies related to primitive actions. Our intervention provides automated, user-specific feedback by comparing trainee performance to expert benchmarks and highlighting deviations from optimal execution through understandable proxies for actionable guidance. In a prospective user study with medical students, we compare the impact of XAI-guided feedback against traditional video-based coaching on task outcomes, cognitive load, and trainees' perceptions of AI-assisted learning. Results showed improved cognitive load and confidence post-intervention. While no differences emerged between the two feedback types in reducing performance gaps or practice adjustments, trends in the XAI group revealed desirable effects where participants more closely mimicked expert practice. This work encourages the study of explainable AI in surgical education and the development of data-driven, adaptive feedback mechanisms that could transform learning experiences and competency assessment.

Artificial intelligence-driven adaptive learning systems are reshaping education through data-driven adaptation of learning experiences. Yet many of these systems lack transparency, offering limited insight into how decisions are made. Most explainable AI (XAI) techniques focus on technical outputs but neglect user roles and comprehension. This paper proposes a hybrid framework that integrates traditional XAI techniques with generative AI models and user personalisation to generate multimodal, personalised explanations tailored to user needs. We redefine explainability as a dynamic communication process tailored to user roles and learning goals. We outline the framework's design, key XAI limitations in education, and research directions on accuracy, fairness, and personalisation. Our aim is to move towards explainable AI that enhances transparency while supporting user-centred experiences.