Research Papers

Study of Different Deep Learning Approach with Explainable AI for Screening Patients with COVID-19 Symptoms: Using CT Scan and Chest X-ray Image Dataset

Md Manjurul Ahsan, Kishor Datta Gupta, Mohammad Maminur Islam +3

The outbreak of COVID-19 disease caused more than 100,000 deaths so far in the USA alone. It is necessary to conduct an initial screening of patients with the symptoms of COVID-19 disease to control the spread of the disease. However, it is becoming laborious to conduct the tests with the available testing kits due to the growing number of patients. Some studies proposed CT scan or chest X-ray images as an alternative solution. Therefore, it is essential to use every available resource, instead of either a CT scan or chest X-ray to conduct a large number of tests simultaneously. As a result, this study aims to develop a deep learning-based model that can detect COVID-19 patients with better accuracy both on CT scan and chest X-ray image dataset. In this work, eight different deep learning approaches such as VGG16, InceptionResNetV2, ResNet50, DenseNet201, VGG19, MobilenetV2, NasNetMobile, and ResNet15V2 have been tested on two dataset-one dataset includes 400 CT scan images, and another dataset includes 400 chest X-ray images studied. Besides, Local Interpretable Model-agnostic Explanations (LIME) is used to explain the model's interpretability. Using LIME, test results demonstrate that it is conceivable to interpret top features that should have worked to build a trust AI framework to distinguish between patients with COVID-19 symptoms with other patients.

Understanding intermediate layers of a deep learning model and discovering the driving features of stimuli have attracted much interest, recently. Explainable artificial intelligence (XAI) provides a new way to open an AI black box and makes a transparent and interpretable decision. This paper proposes a new explainable convolutional neural network (XCNN) which represents important and driving visual features of stimuli in an end-to-end model architecture. This network employs encoder-decoder neural networks in a CNN architecture to represent regions of interest in an image based on its category. The proposed model is trained without localization labels and generates a heat-map as part of the network architecture without extra post-processing steps. The experimental results on the CIFAR-10, Tiny ImageNet, and MNIST datasets showed the success of our algorithm (XCNN) to make CNNs explainable. Based on visual assessment, the proposed model outperforms the current algorithms in class-specific feature representation and interpretable heatmap generation while providing a simple and flexible network architecture. The initial success of this approach warrants further study to enhance weakly supervised localization and semantic segmentation in explainable frameworks.

How Much Can I Trust You? -- Quantifying Uncertainties in Explaining Neural Networks

Kirill Bykov, Marina M. -C. Höhne, Klaus-Robert Müller +2

Explainable AI (XAI) aims to provide interpretations for predictions made by learning machines, such as deep neural networks, in order to make the machines more transparent for the user and furthermore trustworthy also for applications in e.g. safety-critical areas. So far, however, no methods for quantifying uncertainties of explanations have been conceived, which is problematic in domains where a high confidence in explanations is a prerequisite. We therefore contribute by proposing a new framework that allows to convert any arbitrary explanation method for neural networks into an explanation method for Bayesian neural networks, with an in-built modeling of uncertainties. Within the Bayesian framework a network's weights follow a distribution that extends standard single explanation scores and heatmaps to distributions thereof, in this manner translating the intrinsic network model uncertainties into a quantification of explanation uncertainties. This allows us for the first time to carve out uncertainties associated with a model explanation and subsequently gauge the appropriate level of explanation confidence for a user (using percentiles). We demonstrate the effectiveness and usefulness of our approach extensively in various experiments, both qualitatively and quantitatively.

The growing influence and decision-making capacities of Autonomous systems and Artificial Intelligence in our lives force us to consider the values embedded in these systems. But how ethics should be implemented into these systems? In this study, the solution is seen on philosophical conceptualization as a framework to form practical implementation model for ethics of AI. To take the first steps on conceptualization main concepts used on the field needs to be identified. A keyword based Systematic Mapping Study (SMS) on the keywords used in AI and ethics was conducted to help in identifying, defying and comparing main concepts used in current AI ethics discourse. Out of 1062 papers retrieved SMS discovered 37 re-occurring keywords in 83 academic papers. We suggest that the focus on finding keywords is the first step in guiding and providing direction for future research in the AI ethics field.

Recent advances in artificial intelligence (AI) speech generation and voice cloning technologies have produced naturalistic speech and accurate voice replication, yet their influence on sociotechnical systems across diverse accents and linguistic traits is not fully understood. This study evaluates two synthetic AI voice services (Speechify and ElevenLabs) through a mixed methods approach using surveys and interviews to assess technical performance and uncover how users' lived experiences influence their perceptions of accent variations in these speech technologies. Our findings reveal technical performance disparities across five regional, English-language accents and demonstrate how current speech generation technologies may inadvertently reinforce linguistic privilege and accent-based discrimination, potentially creating new forms of digital exclusion. Overall, our study highlights the need for inclusive design and regulation by providing actionable insights for developers, policymakers, and organizations to ensure equitable and socially responsible AI speech technologies.

Recent research has developed a number of eXplainable AI (XAI) techniques, such as gradient-based approaches, input perturbation-base methods, and black-box explanation methods. While these XAI techniques can extract meaningful insights from deep learning models, how to properly evaluate them remains an open problem. The most widely used approach is to perturb or even remove what the XAI method considers to be the most important features in an input and observe the changes in the output prediction. This approach, although straightforward, suffers the Out-of-Distribution (OOD) problem as the perturbed samples may no longer follow the original data distribution. A recent method RemOve And Retrain (ROAR) solves the OOD issue by retraining the model with perturbed samples guided by explanations. However, using the model retrained based on XAI methods to evaluate these explainers may cause information leakage and thus lead to unfair comparisons. We propose Fine-tuned Fidelity (F-Fidelity), a robust evaluation framework for XAI, which utilizes i) an explanation-agnostic fine-tuning strategy, thus mitigating the information leakage issue, and ii) a random masking operation that ensures that the removal step does not generate an OOD input. We also design controlled experiments with state-of-the-art (SOTA) explainers and their degraded version to verify the correctness of our framework. We conduct experiments on multiple data modalities, such as images, time series, and natural language. The results demonstrate that F-Fidelity significantly improves upon prior evaluation metrics in recovering the ground-truth ranking of the explainers. Furthermore, we show both theoretically and empirically that, given a faithful explainer, F-Fidelity metric can be used to compute the sparsity of influential input components, i.e., to extract the true explanation size.

The successful application of machine learning (ML) in catalyst design relies on high-quality and diverse data to ensure effective generalization to novel compositions, thereby aiding in catalyst discovery. However, due to complex interactions, catalyst design has long relied on trial-and-error, a costly and labor-intensive process leading to scarce data that is heavily biased towards undesired, low-yield catalysts. Despite the rise of ML in this field, most efforts have not focused on dealing with the challenges presented by such experimental data. To address these challenges, we introduce a robust machine learning and explainable AI (XAI) framework to accurately classify the catalytic yield of various compositions and identify the contributions of individual components. This framework combines a series of ML practices designed to handle the scarcity and imbalance of catalyst data. We apply the framework to classify the yield of various catalyst compositions in oxidative methane coupling, and use it to evaluate the performance of a range of ML models: tree-based models, logistic regression, support vector machines, and neural networks. These experiments demonstrate that the methods used in our framework lead to a significant improvement in the performance of all but one of the evaluated models. Additionally, the decision-making process of each ML model is analyzed by identifying the most important features for predicting catalyst performance using XAI methods. Our analysis found that XAI methods, providing class-aware explanations, such as Layer-wise Relevance Propagation, identified key components that contribute specifically to high-yield catalysts. These findings align with chemical intuition and existing literature, reinforcing their validity. We believe that such insights can assist chemists in the development and identification of novel catalysts with superior performance.

Lung diseases remain a critical global health concern, and it's crucial to have accurate and quick ways to diagnose them. This work focuses on classifying different lung diseases into five groups: viral pneumonia, bacterial pneumonia, COVID, tuberculosis, and normal lungs. Employing advanced deep learning techniques, we explore a diverse range of models including CNN, hybrid models, ensembles, transformers, and Big Transfer. The research encompasses comprehensive methodologies such as hyperparameter tuning, stratified k-fold cross-validation, and transfer learning with fine-tuning.Remarkably, our findings reveal that the Xception model, fine-tuned through 5-fold cross-validation, achieves the highest accuracy of 96.21\%. This success shows that our methods work well in accurately identifying different lung diseases. The exploration of explainable artificial intelligence (XAI) methodologies further enhances our understanding of the decision-making processes employed by these models, contributing to increased trust in their clinical applications.

Explainable Artificial Intelligence (XAI) is a young but very promising field of research. Unfortunately, the progress in this field is currently slowed down by divergent and incompatible goals. We separate various threads tangled within the area of XAI into two complementary cultures of human/value-oriented explanations (BLUE XAI) and model/validation-oriented explanations (RED XAI). This position paper argues that the area of RED XAI is currently under-explored, i.e., more methods for explainability are desperately needed to question models (e.g., extract knowledge from well-performing models as well as spotting and fixing bugs in faulty models), and the area of RED XAI hides great opportunities and potential for important research necessary to ensure the safety of AI systems. We conclude this paper by presenting promising challenges in this area.

Black-box deep learning approaches have showcased significant potential in the realm of medical image analysis. However, the stringent trustworthiness requirements intrinsic to the medical field have catalyzed research into the utilization of Explainable Artificial Intelligence (XAI), with a particular focus on concept-based methods. Existing concept-based methods predominantly apply concept annotations from a single perspective (e.g., global level), neglecting the nuanced semantic relationships between sub-regions and concepts embedded within medical images. This leads to underutilization of the valuable medical information and may cause models to fall short in harmoniously balancing interpretability and performance when employing inherently interpretable architectures such as Concept Bottlenecks. To mitigate these shortcomings, we propose a multi-modal explainable disease diagnosis framework that meticulously aligns medical images and clinical-related concepts semantically at multiple strata, encompassing the image level, token level, and concept level. Moreover, our method allows for model intervention and offers both textual and visual explanations in terms of human-interpretable concepts. Experimental results on three skin image datasets demonstrate that our method, while preserving model interpretability, attains high performance and label efficiency for concept detection and disease diagnosis.

AI Audit: A Card Game to Reflect on Everyday AI Systems

Safinah Ali, Vishesh Kumar, Cynthia Breazeal

An essential element of K-12 AI literacy is educating learners about the ethical and societal implications of AI systems. Previous work in AI ethics literacy have developed curriculum and classroom activities that engage learners in reflecting on the ethical implications of AI systems and developing responsible AI. There is little work in using game-based learning methods in AI literacy. Games are known to be compelling media to teach children about complex STEM concepts. In this work, we developed a competitive card game for middle and high school students called "AI Audit" where they play as AI start-up founders building novel AI-powered technology. Players can challenge other players with potential harms of their technology or defend their own businesses by features that mitigate these harms. The game mechanics reward systems that are ethically developed or that take steps to mitigate potential harms. In this paper, we present the game design, teacher resources for classroom deployment and early playtesting results. We discuss our reflections about using games as teaching tools for AI literacy in K-12 classrooms.

Logic for Explainable AI

Adnan Darwiche

A central quest in explainable AI relates to understanding the decisions made by (learned) classifiers. There are three dimensions of this understanding that have been receiving significant attention in recent years. The first dimension relates to characterizing conditions on instances that are necessary and sufficient for decisions, therefore providing abstractions of instances that can be viewed as the "reasons behind decisions." The next dimension relates to characterizing minimal conditions that are sufficient for a decision, therefore identifying maximal aspects of the instance that are irrelevant to the decision. The last dimension relates to characterizing minimal conditions that are necessary for a decision, therefore identifying minimal perturbations to the instance that yield alternate decisions. We discuss in this tutorial a comprehensive, semantical and computational theory of explainability along these dimensions which is based on some recent developments in symbolic logic. The tutorial will also discuss how this theory is particularly applicable to non-symbolic classifiers such as those based on Bayesian networks, decision trees, random forests and some types of neural networks.