Research Papers

Lung cancer remains one of the leading causes of cancer-related mortality worldwide. Conventional computed tomography (CT) imaging, while essential for detection and staging, has limitations in distinguishing benign from malignant lesions and providing interpretable diagnostic insights. To address this challenge, this study proposes a dual-modal artificial intelligence framework that integrates CT radiology with hematoxylin and eosin (H&E) histopathology for lung cancer diagnosis and subtype classification. The system employs convolutional neural networks to extract radiologic and histopathologic features and incorporates clinical metadata to improve robustness. Predictions from both modalities are fused using a weighted decision-level integration mechanism to classify adenocarcinoma, squamous cell carcinoma, large cell carcinoma, small cell lung cancer, and normal tissue. Explainable AI techniques including Grad-CAM, Grad-CAM++, Integrated Gradients, Occlusion, Saliency Maps, and SmoothGrad are applied to provide visual interpretability. Experimental results show strong performance with accuracy up to 0.87, AUROC above 0.97, and macro F1-score of 0.88. Grad-CAM++ achieved the highest faithfulness and localization accuracy, demonstrating strong correspondence with expert-annotated tumor regions. These results indicate that multimodal fusion of radiology and histopathology can improve diagnostic performance while maintaining model transparency, suggesting potential for future clinical decision support systems in precision oncology.

While Large Language Models (LLMs) demonstrate increasingly sophisticated affective capabilities, the internal mechanisms by which they process complex emotions remain unclear. Existing interpretability approaches often treat models as black boxes or focus on coarse-grained basic emotions, leaving the cognitive structure of more complex affective states underexplored. To bridge this gap, we propose a Cognitive Reverse-Engineering framework based on Representation Engineering (RepE) to analyze social-comparison jealousy. By combining appraisal theory with subspace orthogonalization, regression-based weighting, and bidirectional causal steering, we isolate and quantify two psychological antecedents of jealousy, Superiority of Comparison Person and Domain Self-Definitional Relevance, and examine their causal effects on model judgments. Experiments on eight LLMs from the Llama, Qwen, and Gemma families suggest that models natively encode jealousy as a structured linear combination of these constituent factors. Their internal representations are broadly consistent with the human psychological construct, treating Superiority as the foundational trigger and Relevance as the ultimate intensity multiplier. Our framework also demonstrates that toxic emotional states can be mechanically detected and surgically suppressed, suggesting a possible route toward representational monitoring and intervention for AI safety in multi-agent environments.

As companies enter the race for agentic AI adoption, fears surface around agentic autonomy and its subsequent risks. These fears compound as companies scale their agentic AI adoption with low-code applications, without a comparable scaling in their governance processes and expertise resulting in a phenomenon known as "Agent Sprawl". While shadow AI tools can help with agentic discovery and identification, few observability tools offer insights into the agents' configuration and settings or the decision-making process during agent-to-agent communication and orchestration. This paper explores AI governance professionals' concerns in enterprise settings, while offering design-time and runtime explainability techniques as suggested by AI governance experts for addressing those fears. Finally, we provide a preliminary prototype of an Agentic AI Card that can help companies feel at ease deploying agents at scale.

Digital Guardians: The Past and The Future of Cyber-Physical Resilience

Saurabh Bagchi, Hyunseung Kim, Tarek Abdelzaher +20

Resilience in cyber-physical systems (CPS) is the fundamental ability to maintain safety and critical functionality despite adverse "perturbations," which includes security attacks, environmental disruptions, and hardware or software failures. This survey provides a comprehensive review of CPS resilience, framing the field through five interconnected themes that are required in an integrated whole to achieve real-world resilience. The article first posits that resilience is a system-wide property emerging from interactions between hardware, software, and human users. Second, it addresses the challenges of learning-enabled CPS, which often operate in data-scarce environments characterized by imbalanced or noisy data, requiring innovative solutions like synthetic data generation and foundation model adaptation. Third, the survey examines proactive measures for resilience, which include distinctive aspects of verification, testing, and redundancy. Fourth, it explores recovery mechanisms, moving beyond traditional fault models to design "just good enough" recovery strategies that prioritize safety-critical functions during perturbations. Finally, it highlights the central role of the human, focusing on the different levels of human intervention, the necessity of trust calibration, and the requirement for explainable AI to support human-CPS teaming. These themes are illustrated through representative application domains, primarily Connected and Autonomous Transportation Systems (CATS) and Medical CPS (MCPS). By integrating the five interconnected themes, this survey provides a systematic roadmap for achieving the resilient CPS in increasingly complex and adversarial environments.

Mapping the spatial distribution of species is essential for conservation policy and invasive species management. Species distribution models (SDMs) are the primary tools for this task, serving two purposes: achieving robust predictive performance while providing ecological insights into the driving factors of distribution. However, the increasing complexity of deep learning SDMs has made extracting these insights more challenging. To reconcile these objectives, we propose the first implementation of concept-based Explainable AI (XAI) for SDMs. We leverage the Robust TCAV (Testing with Concept Activation Vectors) methodology to quantify the influence of landscape concepts on model predictions. To enable this, we provide a new open-access landscape concept dataset derived from high-resolution multispectral and LiDAR drone imagery. It includes 653 patches across 15 distinct landscape concepts and 1,450 random reference patches, designed to suit a wide range of species. We demonstrate this approach through a case study of two aquatic insects, Plecoptera and Trichoptera, using two Convolutional Neural Networks and one Vision Transformer. Results show that concept-based XAI helps validate SDMs against expert knowledge while uncovering novel associations that generate new ecological hypotheses. Robust TCAV also provides landscape-level information, useful for policy-making and land management. Code and datasets are publicly available.

Human activity recognition (HAR) has become a key component of intelligent systems for healthcare monitoring, assistive living, smart environments, and human-computer interaction. Although deep learning has substantially improved HAR performance on multivariate sensor data, the resulting models often remain opaque, limiting trust, reliability, and real-world deployment. Explainable artificial intelligence (XAI) has therefore emerged as a critical direction for making HAR systems more transparent and human-centered. This paper presents a comprehensive review of explainable HAR methods across wearable, ambient, physiological, and multimodal sensing settings. We introduce a unified perspective that separates conceptual dimensions of explainability from algorithmic explanation mechanisms, reducing ambiguities in prior surveys. Building on this distinction, we present a mechanism-centric taxonomy of XAI-HAR methods covering major explanation paradigms. The review examines how these methods address the temporal, multimodal, and semantic complexities of HAR, and summarize their interpretability objectives, explanation targets, and limitations. In addition, we discuss current evaluation practices, highlight key challenges in achieving reliable and deployable XAI-HAR, and outline directions toward trustworthy activity recognition systems that better support human understanding and decision-making.

Neural networks deliver impressive predictive performance across a variety of tasks, but they are often opaque in their decision-making processes. Despite a growing interest in mechanistic interpretability, tools for systematically exploring the representations learned by neural networks in general, and tabular foundation models in particular, remain limited. In this work, we introduce ConceptTracer, an interactive application for analyzing neural representations through the lens of human-interpretable concepts. ConceptTracer integrates two information-theoretic measures that quantify concept saliency and selectivity, enabling researchers and practitioners to identify neurons that respond strongly to individual concepts. We demonstrate the utility of ConceptTracer on representations learned by TabPFN and show that our approach facilitates the discovery of interpretable neurons. Together, these capabilities provide a practical framework for investigating how neural networks like TabPFN encode concept-level information. ConceptTracer is available at https://github.com/ml-lab-htw/concept-tracer.

In this growing age of data and technology, large black-box models are becoming the norm due to their ability to handle vast amounts of data and learn incredibly complex data patterns. The deficiency of these methods, however, is their inability to explain the prediction process, making them untrustworthy and their use precarious in high-stakes situations. SHapley Additive exPlanations (SHAP) analysis is an explainable AI method growing in popularity for its ability to explain model predictions in terms of the original features. For each sample and feature in the data set, an associated SHAP value quantifies the contribution of that feature to the prediction of that sample. Analysis of these SHAP values provides valuable insight into the model's decision-making process, which can be leveraged to create data-driven solutions. The interpretation of these SHAP values, however, is model-dependent, so there does not exist a universal analysis procedure. To aid in these efforts, we present a detailed investigation of SHAP analysis across various machine learning models and data sets. In uncovering the details and nuance behind SHAP analysis, we hope to empower analysts in this less-explored territory. We also present a novel generalization of the waterfall plot to the multi-classification problem.

We present a neurosymbolic approach, i.e. combine symbolic and subsymbolic artificial intelligence, to validating offer documents in regulated public institutions. We employ a language model to extract information and then aggregate it with an LTN (Logic Tensor Network) to make an auditable decision. In regulated public institutions, decisions must be made in a manner that is both factually correct and legally verifiable. Our neurosymbolic approach allows existing domain-specific knowledge to be linked to the semantic text understanding of language models. The decisions resulting from our pipeline can be justified by predicate values, rule truth values, and corresponding text passages. Our experiments on a real corpus show that the proposed pipeline achieves performance comparable to existing models, but its key advantage lies in its interpretability, modular predicate extraction, and explicit support for XAI (Explainable AI).

Deep Neural Networks (DNNs) are increasingly utilized in high-stakes domains like medical diagnostics and autonomous driving where model reliability is critical. However, the research landscape for ensuring this reliability is terminologically fractured across communities that pursue the same goal of ensuring models rely on causally relevant features rather than confounding signals. While frameworks such as distributionally robust optimization (DRO), invariant risk minimization (IRM), shortcut learning, simplicity bias, and the Clever Hans effect all address model failure due to spurious correlations, researchers typically only reference work within their own domains. This reproducibility study unifies these perspectives through a comparative analysis of correction methods under challenging constraints like limited data availability and severe subgroup imbalance. We evaluate recently proposed correction methods based on explainable artificial intelligence (XAI) techniques alongside popular non-XAI baselines using both synthetic and real-world datasets. Findings show that XAI-based methods generally outperform non-XAI approaches, with Counterfactual Knowledge Distillation (CFKD) proving most consistently effective at improving generalization. Our experiments also reveal that the practical application of many methods is hindered by a dependency on group labels, as manual annotation is often infeasible and automated tools like Spectral Relevance Analysis (SpRAy) struggle with complex features and severe imbalance. Furthermore, the scarcity of minority group samples in validation sets renders model selection and hyperparameter tuning unreliable, posing a significant obstacle to the deployment of robust and trustworthy models in safety-critical areas.

As large language models (LLMs) continue to improve and see further integration into software systems, so does the need to understand the conditions in which they will perform. We contribute a statistical framework for understanding the impact of specific prompt features on LLM performance. The approach extends previous explainable artificial intelligence (XAI) methods specifically to inspect LLMs by fitting regression models relating portions of the prompt to LLM evaluation. We apply our method to compare how two open-source models, Mistral-7B and GPT-OSS-20B, leverage the prompt to perform a simple arithmetic problem. Regression models of individual prompt portions explain 72% and 77% of variation in model performances, respectively. We find misinformation in the form of incorrect example query-answer pairs impedes both models from solving the arithmetic query, though positive examples do not find significant variability in the impact of positive and negative instructions - these prompts have contradictory effects on model performance. The framework serves as a tool for decision makers in critical scenarios to gain granular insight into how the prompt influences an LLM to solve a task.

Agriculture is increasingly challenged by climate change, soil degradation, and resource depletion, and hence requires advanced data-driven crop classification and recommendation solutions. This work presents an explainable ensemble learning paradigm that fuses optimized feature pyramids, deep networks, self-attention mechanisms, and residual networks for bolstering crop suitability predictions based on soil characteristics (e.g., pH, nitrogen, potassium) and climatic conditions (e.g., temperature, rainfall). With a dataset comprising 3,867 instances and 29 features from the Ethiopian Agricultural Transformation Agency and NASA, the paradigm leverages preprocessing methods such as label encoding, outlier removal using IQR, normalization through StandardScaler, and SMOTE for balancing classes. A range of machine learning models such as Logistic Regression, K-Nearest Neighbors, Support Vector Machines, Decision Trees, Random Forest, Gradient Boosting, and a new Relative Error Support Vector Machine are compared, with hyperparameter tuning through Grid Search and cross-validation. The suggested "Final Ensemble" meta-ensemble design outperforms with 98.80% accuracy, precision, recall, and F1-score, compared to individual models such as K-Nearest Neighbors (95.56% accuracy). Explainable AI methods, such as SHAP and permutation importance, offer actionable insights, highlighting critical features such as soil pH, nitrogen, and zinc. The paradigm addresses the gap between intricate ML models and actionable agricultural decision-making, fostering sustainability and trust in AI-powered recommendations