Research Papers

The rapid growth of YouTube Shorts, now serving over 2 billion monthly users, reflects a global shift toward short-form video as a dominant mode of online content consumption. This study investigates algorithmic bias in YouTube Shorts' recommendation system by analyzing how watch-time duration, topic sensitivity, and engagement metrics influence content visibility and drift. We focus on three content domains: the South China Sea dispute, the 2024 Taiwan presidential election, and general YouTube Shorts content. Using generative AI models, we classified 685,842 videos across relevance, topic category, and emotional tone. Our results reveal a consistent drift away from politically sensitive content toward entertainment-focused videos. Emotion analysis shows a systematic preference for joyful or neutral content, while engagement patterns indicate that highly viewed and liked videos are disproportionately promoted, reinforcing popularity bias. This work provides the first comprehensive analysis of algorithmic drift in YouTube Shorts based on textual content, emotional tone, topic categorization, and varying watch-time conditions. These findings offer new insights into how algorithmic design shapes content exposure, with implications for platform transparency and information diversity.

Quantifying Cross-Attention Interaction in Transformers for Interpreting TCR-pMHC Binding

Jiarui Li, Zixiang Yin, Haley Smith +3

CD8+ "killer" T cells and CD4+ "helper" T cells play a central role in the adaptive immune system by recognizing antigens presented by Major Histocompatibility Complex (pMHC) molecules via T Cell Receptors (TCRs). Modeling binding between T cells and the pMHC complex is fundamental to understanding basic mechanisms of human immune response as well as in developing therapies. While transformer-based models such as TULIP have achieved impressive performance in this domain, their black-box nature precludes interpretability and thus limits a deeper mechanistic understanding of T cell response. Most existing post-hoc explainable AI (XAI) methods are confined to encoder-only, co-attention, or model-specific architectures and cannot handle encoder-decoder transformers used in TCR-pMHC modeling. To address this gap, we propose Quantifying Cross-Attention Interaction (QCAI), a new post-hoc method designed to interpret the cross-attention mechanisms in transformer decoders. Quantitative evaluation is a challenge for XAI methods; we have compiled TCR-XAI, a benchmark consisting of 274 experimentally determined TCR-pMHC structures to serve as ground truth for binding. Using these structures we compute physical distances between relevant amino acid residues in the TCR-pMHC interaction region and evaluate how well our method and others estimate the importance of residues in this region across the dataset. We show that QCAI achieves state-of-the-art performance on both interpretability and prediction accuracy under the TCR-XAI benchmark.

While artificial intelligence (AI) is advancing rapidly and mastering increasingly complex problems with astonishing performance, the safety assurance of such systems is a major concern. Particularly in the context of safety-critical, real-world cyber-physical systems, AI promises to achieve a new level of autonomy but is hampered by a lack of safety assurance. While data-driven control takes up recent developments in AI to improve control systems, control theory in general could be leveraged to improve AI safety. Therefore, this article outlines a new perspective on AI safety based on an interdisciplinary interpretation of the underlying data-generation process and the respective abstraction by AI systems in a system theory-inspired and system analysis-driven manner. In this context, the new perspective, also referred to as data control, aims to stimulate AI engineering to take advantage of existing safety analysis and assurance in an interdisciplinary way to drive the paradigm of data control. Following a top-down approach, a generic foundation for safety analysis and assurance is outlined at an abstract level that can be refined for specific AI systems and applications and is prepared for future innovation.

Less Data, More Security: Advancing Cybersecurity LLMs Specialization via Resource-Efficient Domain-Adaptive Continuous Pre-training with Minimal Tokens

Salahuddin Salahuddin, Ahmed Hussain, Jussi Löppönen +1

The increasing scale of AI workloads demands High-Performance Computing (HPC) infrastructure and training methodologies that are both scalable and sustainable. While Large Language Models (LLMs) demonstrate exceptional natural language capabilities, general-purpose models often lack the specialized domain knowledge necessary for effective cybersecurity analysis. We investigate Domain-Adaptive Continuous Pretraining (DAP) as a scalable, resource-efficient methodology for enhancing cybersecurity understanding in pretrained LLMs, implemented through a distributed Fully Sharded Data Parallel (FSDP) pipeline across multi-node GPU clusters. We systematically adapted three decoder-based architectures -- Llama-3.1-8B, DeepSeek-R1-Distill-Qwen-14B, and Llama-3.3-70B-Instruct -- using a curated 126-million-word cybersecurity corpus from standards, academic literature, and technical documentation. Evaluation across three cybersecurity benchmarks -- CTI-MCQ, CyberMetric, and SecEval -- demonstrates consistent improvements post-adaptation. Notably, our Llama-3.3-70B-Ins-DAP model achieves state-of-the-art performance with accuracies of 0.718, 0.933, and 0.864, respectively, surpassing parameter-efficient baselines and specialized models including Llama-Primus-Base (trained on 2.77 billion tokens) and Foundation-Sec-8B (trained on 5 billion tokens), despite utilizing only 118.8 million tokens -- representing a 23-to-42-fold reduction in training data. Targeted continuous pretraining via scalable HPC infrastructure enables effective cybersecurity domain adaptation with a substantially reduced computational and energy footprint, supporting specialized AI assistants in threat analysis, vulnerability assessment, and security documentation, while advancing sustainable and responsible AI development.

Artificial Intelligence (AI) is rapidly being integrated into critical systems across various domains, from healthcare to autonomous vehicles. While its integration brings immense benefits, it also introduces significant risks, including those arising from AI misuse. Within the discourse on managing these risks, the terms "AI Safety" and "AI Security" are often used, sometimes interchangeably, resulting in conceptual confusion. This paper aims to demystify the distinction and delineate the precise research boundaries between AI Safety and AI Security. We provide rigorous definitions, outline their respective research focuses, and explore their interdependency, including how security breaches can precipitate safety failures and vice versa. Using clear analogies from message transmission and building construction, we illustrate these distinctions. Clarifying these boundaries is crucial for guiding precise research directions, fostering effective cross-disciplinary collaboration, enhancing policy effectiveness, and ultimately, promoting the deployment of trustworthy AI systems.

Healthcare 5.0 integrates Artificial Intelligence (AI), the Internet of Things (IoT), real-time monitoring, and human-centered design toward personalized medicine and predictive diagnostics. However, the increasing reliance on interconnected medical technologies exposes them to cyber threats. Meanwhile, current AI-driven cybersecurity models often neglect biomedical data, limiting their effectiveness and interpretability. This study addresses this gap by applying eXplainable AI (XAI) to a Healthcare 5.0 dataset that integrates network traffic and biomedical sensor data. Classification outputs indicate that XGBoost achieved 99% F1-score for benign and data alteration, and 81% for spoofing. Explainability findings reveal that network data play a dominant role in intrusion detection whereas biomedical features contributed to spoofing detection, with temperature reaching a Shapley values magnitude of 0.37.

Cooperative game theory has become a cornerstone of post-hoc interpretability in machine learning, largely through the use of Shapley values. Yet, despite their widespread adoption, Shapley-based methods often rest on axiomatic justifications whose relevance to feature attribution remains debatable. In this paper, we revisit cooperative game theory from an interpretability perspective and argue for a broader and more principled use of its tools. We highlight two general families of efficient allocations, the Weber and Harsanyi sets, that extend beyond Shapley values and offer richer interpretative flexibility. We present an accessible overview of these allocation schemes, clarify the distinction between value functions and aggregation rules, and introduce a three-step blueprint for constructing reliable and theoretically-grounded feature attributions. Our goal is to move beyond fixed axioms and provide the XAI community with a coherent framework to design attribution methods that are both meaningful and robust to shifting methodological trends.

Despite promising developments in Explainable Artificial Intelligence, the practical value of XAI methods remains under-explored and insufficiently validated in real-world settings. Robust and context-aware evaluation is essential, not only to produce understandable explanations but also to ensure their trustworthiness and usability for intended users, but tends to be overlooked because of no clear guidelines on how to design an evaluation with users. This study addresses this gap with two main goals: (1) to develop a framework of well-defined, atomic properties that characterise the user experience of XAI in healthcare; and (2) to provide clear, context-sensitive guidelines for defining evaluation strategies based on system characteristics. We conducted a systematic review of 82 user studies, sourced from five databases, all situated within healthcare settings and focused on evaluating AI-generated explanations. The analysis was guided by a predefined coding scheme informed by an existing evaluation framework, complemented by inductive codes developed iteratively. The review yields three key contributions: (1) a synthesis of current evaluation practices, highlighting a growing focus on human-centred approaches in healthcare XAI; (2) insights into the interrelations among explanation properties; and (3) an updated framework and a set of actionable guidelines to support interdisciplinary teams in designing and implementing effective evaluation strategies for XAI systems tailored to specific application contexts.

Evaluating feature attribution methods represents a critical challenge in explainable AI (XAI), as researchers typically rely on perturbation-based metrics when ground truth is unavailable. However, recent work reveals that these evaluation metrics can show different performance across predicted classes within the same dataset. These "class-dependent evaluation effects" raise questions about whether perturbation analysis reliably measures attribution quality, with direct implications for XAI method development and evaluation trustworthiness. We investigate under which conditions these class-dependent effects arise by conducting controlled experiments with synthetic time series data where ground truth feature locations are known. We systematically vary feature types and class contrasts across binary classification tasks, then compare perturbation-based degradation scores with ground truth-based precision-recall metrics using multiple attribution methods. Our experiments demonstrate that class-dependent effects emerge with both evaluation approaches, even in simple scenarios with temporally localized features, triggered by basic variations in feature amplitude or temporal extent between classes. Most critically, we find that perturbation-based and ground truth metrics frequently yield contradictory assessments of attribution quality across classes, with weak correlations between evaluation approaches. These findings suggest that researchers should interpret perturbation-based metrics with care, as they may not always align with whether attributions correctly identify discriminating features. By showing this disconnect, our work points toward reconsidering what attribution evaluation actually measures and developing more rigorous evaluation methods that capture multiple dimensions of attribution quality.

The relationship between humans and artificial intelligence is no longer science fiction -- it's a growing reality reshaping how we live and work. AI has moved beyond research labs into everyday life, powering customer service chats, personalizing travel, aiding doctors in diagnosis, and supporting educators. What makes this moment particularly compelling is AI's increasing collaborative nature. Rather than replacing humans, AI augments our capabilities -- automating routine tasks, enhancing decisions with data, and enabling creativity in fields like design, music, and writing. The future of work is shifting toward AI agents handling tasks autonomously, with humans as supervisors, strategists, and ethical stewards. This flips the traditional model: instead of humans using AI as a tool, intelligent agents will operate independently within constraints, managing everything from scheduling and customer service to complex workflows. Humans will guide and fine-tune these agents to ensure alignment with goals, values, and context. This shift offers major benefits -- greater efficiency, faster decisions, cost savings, and scalability. But it also brings risks: diminished human oversight, algorithmic bias, security flaws, and a widening skills gap. To navigate this transition, organizations must rethink roles, invest in upskilling, embed ethical principles, and promote transparency. This paper examines the technological and organizational changes needed to enable responsible adoption of AI-first systems -- where autonomy is balanced with human intent, oversight, and values.

Infertility has a considerable impact on individuals' quality of life, affecting them socially and psychologically, with projections indicating a rise in the upcoming years. In vitro fertilization (IVF) emerges as one of the primary techniques within economically developed nations, employed to address the rising problem of low fertility. Expert embryologists conventionally grade embryos by reviewing blastocyst images to select the most optimal for transfer, yet this process is time-consuming and lacks efficiency. Blastocyst images provide a valuable resource for assessing embryo viability. In this study, we introduce an explainable artificial intelligence (XAI) framework for classifying embryos, employing a fusion of convolutional neural network (CNN) and long short-term memory (LSTM) architecture, referred to as CNN-LSTM. Utilizing deep learning, our model achieves high accuracy in embryo classification while maintaining interpretability through XAI.

The United States and China are among the world's top players in the development of advanced artificial intelligence (AI) systems, and both are keen to lead in global AI governance and development. A look at U.S. and Chinese policy landscapes reveals differences in how the two countries approach the governance of general-purpose artificial intelligence (GPAI) systems. Three areas of divergence are notable for policymakers: the focus of domestic AI regulation, key principles of domestic AI regulation, and approaches to implementing international AI governance. As AI development continues, global conversation around AI has warned of global safety and security challenges posed by GPAI systems. Cooperation between the United States and China might be needed to address these risks, and understanding the implications of these differences might help address the broader challenges for international cooperation between the United States and China on AI safety and security.